World AMR Awareness Week

“Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to antimicrobial agents. As a result of drug resistance, antibiotics and other antimicrobial agents become ineffective and infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness and death.

The World AMR Awareness Week (WAAW) is a global campaign to raise awareness and understanding of AMR and promote best practices among One Health stakeholders to reduce the emergence and spread of drug-resistant infections. WAAW is celebrated from 18-24 November every year.

The theme for the World AMR Awareness Week (WAAW) 2024 is “Educate. Advocate. Act now.” This theme was chosen based on feedback from an online survey among stakeholders from the human, animal, plant, and environmental health sectors, which collected nearly 200 responses globally.”

WHO, World AMR Awareness Week 2024

Enjoy this special collection of calls for papers, Special Issues, and article selections in celebration of World AMR Awareness Week 2024.

Call for Papers

• Call for Papers: Epidemiology, antimicrobial resistance (AMR), virulence, and control of Klebsiella pneumoniae, a bacterial pathogen with high clinical significance opens in new tab/window Submission Deadline: 31 March 2025 Microbiological Research

Special Issues

• Special Issue: Past, Present and Future of Antifungals: Advancements in Mechanisms of Action and Resistance opens in new tab/window Current Research in Microbial Sciences

• Special Issue on Antimicrobial Resistance opens in new tab/window Infection, Disease & Health

• Special issue: Genetic and environmental regulation of antimicrobial resistance opens in new tab/window Microbiological Research

Article collections

Cell Chemical Biology

• SARS-CoV-2 resistance to monoclonal antibodies and small-molecule drugs opens in new tab/window

• Targeting cap1 RNA methyltransferases as an antiviral strategy opens in new tab/window

• Modifying the antiviral innate immune response by selective writing, erasing, and reading of m6A on viral and cellular RNA opens in new tab/window

• PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication opens in new tab/window

• Discovery of antibiotics that selectively kill metabolically dormant bacteria opens in new tab/window

• Selective targeting of Plasmodium falciparum Hsp90 disrupts the 26S proteasome opens in new tab/window

• Discovery of dual-active ethionamide boosters inhibiting the Mycobacterium tuberculosis ESX-1 secretion system opens in new tab/window

Cell Host & Microbe

• Antibiotic resistance: A key microbial survival mechanism that threatens public health opens in new tab/window

• Variability in cell division among anatomical sites shapes Escherichia coli antibiotic survival in a urinary tract infection mouse model opens in new tab/window

• Host stress drives tolerance and persistence: The bane of anti-microbial therapeutics opens in new tab/window

• Susceptible bacteria can survive antibiotic treatment in the mammalian gastrointestinal tract without evolving resistance opens in new tab/window

• Fungicide-tolerant persister formation during cryptococcal pulmonary infection opens in new tab/window

Cell Reports

• In situ chemoproteomic profiling reveals itaconate inhibits de novo purine biosynthesis in pathogens opens in new tab/window

• Population genomics uncovers global distribution, antimicrobial resistance, and virulence genes of the opportunistic pathogen Klebsiella aerogenes opens in new tab/window

• Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii opens in new tab/window

• A platform for predicting mechanism of action based on bacterial transcriptional responses identifies an unusual DNA gyrase inhibitor opens in new tab/window

• YjgM is a crotonyltransferase critical for polymyxin resistance of Escherichia coli opens in new tab/window

Current Research in Microbial Sciences

• Major facilitator superfamily efflux pumps in human pathogens: Role in multidrug resistance and beyond opens in new tab/window

• An updated view of bacterial endophytes as antimicrobial agents against plant and human pathogens opens in new tab/window

• A review on antimicrobial strategies in mitigating biofilm-associated infections on medical implants opens in new tab/window

Food Microbiology

• Antimicrobial effect of garlic against foodborne pathogens in ground mutton opens in new tab/window

• Bacillus subtilis fermented shrimp waste isolated peptide, PVQ9, and its antimicrobial mechanism on four Gram-positive foodborne bacteria opens in new tab/window

• Combined antimicrobial activity of short peptide and phage-derived endolysin against antibiotic-resistant Salmonella Typhimurium opens in new tab/window

• Nanoencapsulation enhances the antimicrobial and antioxidant stability of cyclic lipopeptides for controlling Fusarium graminearum opens in new tab/window

• Antimicrobial activity of essential oil components against Escherichia coli depends on the food components present in a food matrix opens in new tab/window

Infection, Disease & Health

• Prediction of multidrug-resistant bacteria (MDR) hospital-acquired infection (HAI) and colonisation: A systematic review  opens in new tab/window

• Regulating antimicrobial use within hospitals: A qualitative study opens in new tab/window

• Capacity building to address antimicrobial resistance in remote Australia: The inaugural HOT NORTH Antimicrobial Academy opens in new tab/window

• Attitudes to cross infection, nebuliser hygiene and antimicrobial resistance in people with cystic fibrosis: Results of an international survey opens in new tab/window

• Improvement in antibacterial use in intensive care units from Argentina: A quality improvement collaborative process evaluation using Normalization Process Theory opens in new tab/window

Infection Prevention in Practice

• Challenges of implementing antimicrobial stewardship tools in Low to Middle Income Countries (LMICs) opens in new tab/window

• Stewardship: it's going viral opens in new tab/window

• Management of BAME patients with a history of penicillin allergy: barriers to best practice and strategies to overcome these opens in new tab/window

• Antimicrobial resistance as a super wicked problem: how do we engage the public to be part of the solution opens in new tab/window

• Diagnostic stewardship: establishing the role of the hospital nurse to inform local engagement strategies opens in new tab/window

• Prescribing patterns of antimicrobials according to the WHO AWaRe classification at a tertiary referral hospital in the southern highlands of Tanzania opens in new tab/window

Infectious Medicine

• Epidemiology, resistant pathogens, and causes of early death in cases of bloodstream infection in patients with hematological malignancies from 2012–2019 opens in new tab/window

• Advanced approach for antifungal susceptibility and characterization of resistance properties in clinical and environmental isolates of Cryptococcus species complex opens in new tab/window

• Impact of extended-infusion piperacillin-tazobactam in a Canadian community hospital opens in new tab/window

• Pseudomonas aeruginosa: Infections and novel approaches to treatment “Knowing the enemy” the threat of Pseudomonas aeruginosa and exploring novel approaches to treatment opens in new tab/window

• Polymyxin sensitivity/resistance cosmopolitan status, epidemiology and prevalence among O1/O139 and non-O1/non-O139 Vibrio cholerae: A meta-analysis opens in new tab/window

• Metal nanoparticles as inhibitors of enzymes and toxins of multidrug-resistant Staphylococcus aureus opens in new tab/window

• Persistent Nocardia beijingensis infection in a patient with postoperative abscess and misuse of antibiotics in China opens in new tab/window

• Efficacy of new generation biosorbents for the sustainable treatment of antibiotic residues and antibiotic resistance genes from polluted waste effluent opens in new tab/window

• Epidemiological characteristics of ventilator-associated pneumonia in neurosurgery: A 10-year surveillance study in a Chinese tertiary hospital opens in new tab/window

• Characterization of isoniazid resistance and genetic mutations in isoniazid-resistant and rifampicin-susceptible Mycobacterium tuberculosis in China opens in new tab/window

• Evaluating the performance of the Alere PBP2a SA Culture Colony Test with the Vitek 2 Antimicrobial Susceptibility Test Card System as reference standard in coagulase-negative Staphylococcus species opens in new tab/window

iScience

• The ARM repeat domain of hemocyanin interacts with MKK4 to modulate antimicrobial peptides expression opens in new tab/window

• Impedimetric antimicrobial peptide biosensor for the detection of human immunodeficiency virus envelope protein gp120 opens in new tab/window

• Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections opens in new tab/window

• Reactive oxygen species accelerate de novo acquisition of antibiotic resistance in E. coli opens in new tab/window

Journal of Hospital Infection

• Antimicrobial usage and stewardship in a hospice setting opens in new tab/window

• Evaluating antimicrobial utilization in 20 Korean long-term care hospitals: a call to action for antimicrobial stewardship opens in new tab/window

• The role of colonization with resistant Gram-negative bacteria in the treatment of febrile neutropenia after stem cell transplantation opens in new tab/window

• Prescription of Oral Antibiotics and its Appropriateness for Outpatients in a Tertiary-Care Hospital in Korea opens in new tab/window

• Factors associated with antibiotics for respiratory infections in Swiss long-term care facilities opens in new tab/window

Med

• Breastfeeding enrichment of B. longum subsp. infantis mitigates the effect of antibiotics on the microbiota and childhood asthma risk opens in new tab/window

• Refractory Pseudomonas aeruginosa infections treated with phage PASA16: A compassionate use case series opens in new tab/window

• Multidrug-resistant mutations to antiviral and antibody therapy in an immunocompromised patient infected with SARS-CoV-2 opens in new tab/window

• Mycoplasma genitalium in pregnancy, including specific co-infections, is associated with lower birthweight: A prospective cohort study opens in new tab/window

• Neutralizing antibodies after nebulized phage therapy in cystic fibrosis patients opens in new tab/window

• Functional modification of gut bacteria for disease diagnosis and treatment opens in new tab/window

Microbiological Research

• Antimicrobial peptides: Opportunities and challenges in overcoming resistance opens in new tab/window

• Antibiotic adjuvants against multidrug-resistant Gram-negative bacteria: important component of future antimicrobial therapy opens in new tab/window

• Is there a role for intestinal sporobiota in the antimicrobial resistance crisis? opens in new tab/window

Science in One Health

• Multi-modal deep learning based on multi-dimensional and multi-level temporal data can enhance the prognostic prediction for multi-drug resistant pulmonary tuberculosis patients opens in new tab/window

• One Health approaches adapted in low resource settings to address antimicrobial resistance opens in new tab/window

• An agent-based model for collaborative learning to combat antimicrobial resistance: proof of concept based on broiler production in Senegal opens in new tab/window

• Global burden of HIV-negative multidrug- and extensively drug-resistant tuberculosis based on Global Burden of Disease Study 2021 opens in new tab/window

• A bibliometric analysis of One Health approach in research on antimicrobial resistance opens in new tab/window

The Microbe

• Exploring endophytic actinomycetes: A rich reservoir of diverse antimicrobial compounds for combatting global antimicrobial resistance opens in new tab/window

• Physicochemical and metagenomic analysis of samples from the Roman Baths (Bath, UK) reveals high bacterial and archaeal diversity and a potential for antimicrobial discovery opens in new tab/window

• Overview of antimicrobial resistance and mechanisms: The relative status of the past and current opens in new tab/window

Trends in Microbiology

• Balancing act: counteracting adverse drug effects on the microbiome opens in new tab/window

• The role of cyclic nucleotides in bacterial antimicrobial resistance and tolerance opens in new tab/window

• Environmental microbiome, human fungal pathogens, and antimicrobial resistance opens in new tab/window

• Strategies for developing phages into novel antimicrobial tailocins opens in new tab/window

• Forecasting antimicrobial resistance evolution opens in new tab/window

• Plasmid-mediated colistin-resistance genes: mcr opens in new tab/window

Trends in Parasitology

• Peeling the onion: how complex is the artemisinin resistance genetic trait of malaria parasites? opens in new tab/window

• P-glycoproteins in anthelmintic safety, efficacy, and resistance opens in new tab/window

• Pass the boron: benzoxaboroles as antiparasite drugs opens in new tab/window

• The long and winding road towards new treatments against lymphatic filariasis and onchocerciasis opens in new tab/window

• Using our understanding of interactions between helminth metabolism and host immunity to target worm survival opens in new tab/window

• Next-generation sequencing technologies for helminth diagnostics and surveillance in ruminants: shifting diagnostic barriers opens in new tab/window

• Molecular markers for malaria genetic epidemiology: progress and pitfalls opens in new tab/window

• Plasmodium falciparum ring-stage plasticity and drug resistance opens in new tab/window